Caenorhabditis elegans is an instrumental analysis mannequin used to advance our data in areas together with growth, metabolism, and getting old. However, analysis on metabolism and/or different measures of well being/getting old are confounded by the nematode’s food source in the lab, reside E. coli micro organism. Commonly used therapies, together with ultraviolet irradiation and antibiotics, are profitable in stopping bacterial replication, however the micro organism can stay metabolically energetic. The goal of this examine is to develop a metabolically inactive food source for the worms that may enable us to attenuate the confounding results of bacterial metabolism on worm metabolism and getting old.
Our technique is to make use of a paraformaldehyde (PFA) handled E. coli food source and to find out its results on worm well being, metabolism and longevity. We initially decide the bottom potential concentrations of PFA essential to quickly and reproducibly kill micro organism. We then measure numerous points of worm conduct, well beingspan and longevity, together with progress price, food attraction, brood measurement, lifespan and metabolic assessments, comparable to oxygen consumption and metabolomics. Our ensuing knowledge present that worms eat and develop effectively on these micro organism and assist the usage of 0.5% PFA-killed micro organism as a nematode food source for metabolic, drug, and longevity experiments.
Primary goal 1. To assess the consequences of offering grownup sufferers with entry to digital well being information (EHRs) alone or with extra functionalities on a variety of affected person, patient-provider, and well being useful resource consumption outcomes, together with affected person data and understanding, affected person empowerment, affected person adherence, affected person satisfaction with care, adversarial occasions, well being-related high quality of life, well being-related outcomes, psychosocial well being outcomes, well being useful resource consumption, and patient-provider communication. Secondary goal 1. To assess whether or not results of offering grownup sufferers with EHR entry alone versus EHR entry with extra functionalities differ amongst affected person teams in line with age, academic degree, or completely different standing of illness (power or acute).
Adult affected person entry to digital well being information
We included 10 studies with 78 to 4500 members and follow-up from three to 24 months. Nine studies assessed the consequences of EHR with extra functionalities, every addressing a subset of outcomes sought by this assessment. Five studies targeted on sufferers with diabetes mellitus, 4 on sufferers with particular ailments, and one on all sufferers. All studies in contrast EHR entry alone or with extra functionalities plus normal care versus normal care solely. No studies assessing the consequences of EHR entry alone versus EHR entry with extra functionalities had been recognized.
Interventions required a wide range of knowledge throughout the EHR, comparable to affected person historical past, drawback record, treatment, allergy symptoms, and lab outcomes. In addition to EHR entry, eight studies allowed sufferers to share self-documented knowledge, seven provided individualised illness administration features, seven provided academic disease-related info, six supported safe communication, and one provided preventive reminders. Only two studies had been at low or unclear threat of bias throughout domains. Meta-analysis couldn’t be carried out, as members, interventions, and outcomes had been too heterogeneous, and most studies introduced outcomes primarily based on completely different adjustment strategies or variables.
The high quality of proof was rated as low or very low throughout outcomes. Overall variations between intervention and management teams, if any, had been small. The relevance of any small results stays unclear for most outcomes as a result of in most instances, trial authors didn’t outline a minimal clinically essential distinction. Overall, outcomes recommend that the consequences of EHR entry alone and with extra functionalities are principally unsure compared with normal care. Patient data and understanding: very low-quality proof is offered from one examine, so we’re unsure about results of the intervention on affected person data about diabetes and blood glucose testing.
Patient empowerment: low-quality proof from three studies means that the intervention might have little or no impact on affected person empowerment measures. Patient adherence: low-quality proof from two studies means that the intervention might barely enhance adherence to the method of monitoring threat components and preventive providers. Effects on treatment adherence are conflicting in two studies; this will likely or might not enhance to a clinically related diploma. Patient satisfaction with care: low-quality proof from three studies means that the intervention might have little or no impact on affected person satisfaction, with conflicting outcomes.
OKRC01259-96W - MIP-1 gamma ELISA Kit (Mouse)
OKRC01259-96W
Aviva Systems Biology
96Wells
EUR 525
Recombinant Mouse Ccl9/MIP-1 gamma Protein, No Tag
E40MOP2097
EnoGene
20ug
EUR 495
Mouse MIP-1 Gamma (CCL9) Flow Cytometry Assay - Group 4
MX87121
Antigenix America
96 Tests
EUR 270
Mouse CCL9/Mip 1 Gamma PicoKine™ Fast ELISA Kit
FEK1225
BosterBio
96 wells
EUR 570
MIP-1 gamma Recombinant Protein
40-340-0005mg
ProSci
0.005 mg
EUR 311.1
MIP-1 gamma Recombinant Protein
40-340-002mg
ProSci
0.02 mg
EUR 437.1
Mouse Macrophage Inflammatory Protein 1 Gamma-CCL9 ; MIP-1γ-
QY-E21775
Qayee Biotechnology
96T
EUR 420
OOPA00008-5UG - MIP-1 Gamma Protein
OOPA00008-5UG
Aviva Systems Biology
5ug
EUR 70
MIP-1 Macrophage Inflammatory Protein-1 Gamma Mouse Recombinant Protein (CCL9)
PROTP51670
BosterBio
Regular: 20ug
EUR 380.4
Recombinant Murine MIP-1 Gamma (CCL9/CCL10) Protein
PROTP51670-1
BosterBio
20ug
EUR 380.4
MIP1 gamma protein (Mouse)
30R-AM052
Fitzgerald
20 ug
EUR 312
Mouse Monoclonal anti-human PLC gamma -1
hAP-0869
Angio Proteomie
50ug
EUR 400
Mouse anti-IFN gamma Antibody
DL99450A-100ul
DL Develop
100 ul
EUR 299
Mouse anti-IFN gamma Antibody
DL99450A-50ul
DL Develop
50 ul
EUR 210
Anti- Interferon Gamma (IFN-gamma) Mouse Antibody
GWB-BB3356
GenWay Biotech
0.1 mg
Ask for price
Mouse Monoclonal anti-human Interferon gamma (IFN) gamma R1
hAP-0339
Angio Proteomie
100ug
EUR 250
OPSD00094-2UG - Recombinant GRO gamma / MIP-2 beta / CXCL3
OPSD00094-2UG
Aviva Systems Biology
2ug
EUR 108
Mouse anti IFN gamma Monoclonal Antibody
TA354323
Origene Technologies GmbH
100 µg
Ask for price
Mouse anti-Gamma-aminobutyric acid receptor subunit gamma-1 antibody ELISA ki
E01A19099
BlueGene
96T
EUR 700
Mouse Monoclonal anti-human ROR gamma
hAP-0894
Angio Proteomie
50ug
EUR 400
Mouse Monoclonal anti-human PTP gamma
hAP-1086
Angio Proteomie
50ug
EUR 400
Macrophage Inflammatory Protein 1 Gamma (MIP1g) Polyclonal Antibody (Mouse)
4-PAC073Mu01
Cloud-Clone
Mouse Monoclonal anti-human PLC gamma-2
hAP-0871
Angio Proteomie
50ug
EUR 400
Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) Protein
20-abx166104
Abbexa
Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) Protein
abx166104-100g
Abbexa
100 µg
EUR 387.5
Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) Protein
abx166104-200g
Abbexa
200 µg
EUR 550
Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) Protein
abx166104-50g
Abbexa
50 µg
EUR 212.5
Mouse MIP1g(Macrophage Inflammatory Protein 1 Gamma) ELISA Kit
ELK7798-48T
ELK Biotech
48T
Ask for price
Mouse MIP1g(Macrophage Inflammatory Protein 1 Gamma) ELISA Kit
ELK7798-96T
ELK Biotech
96T
Ask for price
Mouse monoclonal anti-human Interferon gamma
gAP-0213
Angio Proteomie
1mg
EUR 450
Macrophage Inflammatory Protein 1 Gamma (MIP1g) Polyclonal Antibody (Mouse), APC
4-PAC073Mu01-APC
Cloud-Clone
Macrophage Inflammatory Protein 1 Gamma (MIP1g) Polyclonal Antibody (Mouse), Cy3
4-PAC073Mu01-Cy3
Cloud-Clone
Macrophage Inflammatory Protein 1 Gamma (MIP1g) Polyclonal Antibody (Mouse), HRP
4-PAC073Mu01-HRP
Cloud-Clone
Macrophage Inflammatory Protein 1 Gamma (MIP1g) Polyclonal Antibody (Mouse), PE
4-PAC073Mu01-PE
Cloud-Clone
Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) CLIA Kit
20-abx496454
Abbexa
Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) ELISA Kit
EKU10475-48T
Biomatik Corporation
48T
EUR 685.72
Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) ELISA Kit
EKU10475-5x96T
Biomatik Corporation
5x96T
EUR 4653.1
Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) ELISA Kit
EKU10475-96T
Biomatik Corporation
96T
EUR 979.6
Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) ELISA Kit
EKU11057-48T
Biomatik Corporation
48T
EUR 571.55
Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) ELISA Kit
EKU11057-5x96T
Biomatik Corporation
5x96T
EUR 3878.38
Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) ELISA Kit
EKU11057-96T
Biomatik Corporation
96T
EUR 816.5
Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) ELISA Kit
EKN51586-48T
Biomatik Corporation
48T
EUR 426.72
Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) ELISA Kit
EKN51586-5x96T
Biomatik Corporation
5x96T
EUR 2895.6
Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) ELISA Kit
EKN51586-96T
Biomatik Corporation
96T
EUR 609.6
Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) ELISA Kit
EKN52168-48T
Biomatik Corporation
48T
EUR 355.6
Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) ELISA Kit
EKN52168-5x96T
Biomatik Corporation
5x96T
EUR 2413
Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) ELISA Kit
EKN52168-96T
Biomatik Corporation
96T
EUR 508
Mouse Macrophage Inflammatory Protein 1 Gamma ELISA Kit (MIP1g)
RK03029
Abclonal
96 Tests
EUR 625.2
Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) ELISA Kit
SEC073Mu-10x96wellstestplate
Cloud-Clone
10x96-wells test plate
EUR 5834.88
Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) ELISA Kit
SEC073Mu-1x48wellstestplate
Cloud-Clone
1x48-wells test plate
EUR 585.7
Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) ELISA Kit
SEC073Mu-1x96wellstestplate
Cloud-Clone
1x96-wells test plate
EUR 785.28
Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) ELISA Kit
SEC073Mu-5x96wellstestplate
Cloud-Clone
5x96-wells test plate
EUR 3173.76
Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) ELISA Kit
4-SEC073Mu
Cloud-Clone
Mouse Monoclonal anti-human PKA C gamma
hAP-0867
Angio Proteomie
50ug
EUR 400
Macrophage Inflammatory Protein 1 Gamma (MIP1g) Polyclonal Antibody (Mouse), FITC
4-PAC073Mu01-FITC
Cloud-Clone
AMPK gamma 1 Mouse mAb
E2222037
EnoGene
100ul
EUR 255
ELISA kit for Mouse MIP1g (Macrophage Inflammatory Protein 1 Gamma)
ELK7798
ELK Biotech
1 plate of 96 wells
EUR 518.4
Rabbit Anti Mouse Mip-1 Alpha Polyclonal Antibody
CPBT-65209RM
Creative Diagnostics
0.1 mg
EUR 1057.2
anti-AMPK gamma 1
YF-PA13985
Abfrontier
100 ug
EUR 483.6
Mouse Monoclonal anti-human 14-3-3 gamma
hAP-0959
Angio Proteomie
50ug
EUR 400
Mouse Anti Rat Interferon Gamma Monoclonal Antibody
CABT-49891MR
Creative Diagnostics
0.1 mg
EUR 670.8
Mouse Anti Cat Interferon Gamma Monoclonal Antibody
CABT-51776MC
Creative Diagnostics
0.5 mg
EUR 1057.2
anti-Laminin gamma 1
YF-PA24068
Abfrontier
50 ul
EUR 400.8
Mouse Anti-Interferon Gamma Antibody (Anti-IFNg) ELISA Kit
EKU12111-48T
Biomatik Corporation
48T
EUR 714.42
Mouse Anti-Interferon Gamma Antibody (Anti-IFNg) ELISA Kit
EKU12111-5x96T
Biomatik Corporation
5x96T
EUR 4847.85
Mouse Anti-Interferon Gamma Antibody (Anti-IFNg) ELISA Kit
EKU12111-96T
Biomatik Corporation
96T
EUR 1020.6
Mouse Anti-Interferon Gamma Antibody (Anti-IFNg) ELISA Kit
EKN53221-48T
Biomatik Corporation
48T
EUR 444.5
Mouse Anti-Interferon Gamma Antibody (Anti-IFNg) ELISA Kit
EKN53221-5x96T
Biomatik Corporation
5x96T
EUR 3016.25
Mouse Anti-Interferon Gamma Antibody (Anti-IFNg) ELISA Kit
EKN53221-96T
Biomatik Corporation
96T
EUR 635
Mouse Anti-Interferon Gamma Antibody (Anti-IFNg) ELISA Kit
abx585791-100g
Abbexa
100 µg
EUR 7650
Mouse Anti-Interferon Gamma Antibody (Anti-IFNg) ELISA Kit
abx585791-10g
Abbexa
10 µg
EUR 850
Mouse Anti-Interferon Gamma Antibody (Anti-IFNg) ELISA Kit
abx585791-50g
Abbexa
50 µg
EUR 4037.5
Rabbit Anti Mouse Interferon Gamma Polyclonal Antibody
CPBT-66975RM
Creative Diagnostics
0.1 mg
EUR 1057.2
Mouse Anti-Human IFN gamma Purified (50 ug)
TA320354
Origene Technologies GmbH
50 µg
Ask for price
Mouse Anti-Human IFN gamma Purified (50 ug)
TA320356
Origene Technologies GmbH
50 µg
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Mouse Anti-Human ROR gamma Purified (25 ug)
TA320414
Origene Technologies GmbH
25 µg
Ask for price
Mouse MIP-1 Alpha Antibody
GWB-36351A
GenWay Biotech
0.1 mg
Ask for price
Mouse Anti Human Interferon Gamma Monoclonal Antibody
CABT-48949MH
Creative Diagnostics
0.2 mg
EUR 889.2
Mouse Anti Human Interferon Gamma Monoclonal Antibody
CABT-48963MH
Creative Diagnostics
0.5 mg
EUR 920.4
Mouse Monoclonal anti-human Interferon (IFN) gamma
hAP-0338
Angio Proteomie
100ug
EUR 250
Mouse Anti Bovine Interferon Gamma Monoclonal Antibody
CABT-51771MB
Creative Diagnostics
0.5 mg
EUR 1057.2
Mouse Anti Bovine Interferon Gamma Monoclonal Antibody
CABT-51773MB
Creative Diagnostics
0.5 mg
EUR 901.2
Mouse Anti Bovine Interferon Gamma Monoclonal Antibody
CABT-51774MB
Creative Diagnostics
0.5 mg
EUR 1057.2
Macrophage Inflammatory Protein 1 Gamma (MIP1g) Polyclonal Antibody (Mouse), APC-Cy7
4-PAC073Mu01-APC-Cy7
Cloud-Clone
Mouse Anti-Human CD64 (Fc gamma Receptor 1) Purified (100 ug)
TA320330
Origene Technologies GmbH
100 µg
Ask for price
Macrophage Inflammatory Protein 1 Gamma (MIP1g) Polyclonal Antibody (Mouse), Biotinylated
4-PAC073Mu01-Biotin
Cloud-Clone
IFN gamma, Interferon gamma, murine (mouse)
RC237-17
Bio Basic
20ug
EUR 125.26
Mouse monoclonal anti-Human CD64 (FC Gamma RI)
hAP-0269
Angio Proteomie
100ug
EUR 250
Mouse Monoclonal anti-human CD64 (FC Gamma RI)
hAP-0269A
Angio Proteomie
50ug
EUR 400
Mouse Monoclonal anti-human CCL4 (MIP-1 beta)
hAP-0251
Angio Proteomie
100ug
EUR 250
Mouse Monoclonal anti-human CCL4 (MIP-1 beta)
hAP-0251A
Angio Proteomie
100ug
EUR 250
Mouse Monoclonal anti-human CD32 (Fc gamma RII)
hAP-0270
Angio Proteomie
100ug
EUR 250
Mouse GRO gamma Antibody
33448-05111
AssayPro
150 ug
EUR 215
Anti- Interferon Gamma (IFN-g) Mouse -BIOTIN Antibody
GWB-78DB1D
GenWay Biotech
0.05 mg
Ask for price
Mouse Monoclonal anti-human CD16 (Fc gamma RIII)
hAP-0271
Angio Proteomie
100ug
EUR 250
Mouse anti-Interferon gamma IgG antibody ELISA kit
E01A22944
BlueGene
96T
EUR 700
MSH, gamma 1 (Human, Rat, Mouse)
043-17
PHOENIX PEPTIDE
500 μg
EUR 58.32
Anti-Laminin gamma-1 antibody
STJ93896
St John's Laboratory
200 µl
EUR 236.4
Mouse Anti-Human TCR gamma/delta mAb (APC) [B1]
E2782284
EnoGene
100tests
EUR 485
Rat Anti Mouse Interferon Gamma Monoclonal Antibody,RPE
CABT-51781RM
Creative Diagnostics
100 TEST
EUR 920.4
Mouse Monoclonal anti-human CD16b (Fc gamma RIIIB)
hAP-0272
Angio Proteomie
100ug
EUR 250
Mouse Anti-Human TCR gamma/delta mAb (FITC) [B1]
E2782283
EnoGene
100tests
EUR 485
Anti-Mouse IFN gamma Receptor-1 Antibody
103-M234
ReliaTech
100 µg
EUR 399
Mouse anti-Gamma-aminobutyric acid receptor subunit gamma-2 antibody ELISA kit
E01A19100
BlueGene
96T
EUR 700
Mouse anti-Gamma-aminobutyric acid receptor subunit gamma-3 antibody ELISA kit
E01A19101
BlueGene
96T
EUR 700
Mouse Actin Gamma 1 ELISA kit
E01A17778
BlueGene
96T
EUR 700
Mouse Actin Gamma 1 ELISA kit
E03A0642-192T
BlueGene
192 tests
EUR 1524
Mouse Actin Gamma 1 ELISA kit
E03A0642-48
BlueGene
1 plate of 48 wells
EUR 624
Mouse Actin Gamma 1 ELISA kit
E03A0642-96
BlueGene
1 plate of 96 wells
EUR 822
MIP1 gamma antibody
70R-MR023
Fitzgerald
50 ug
EUR 312
Rat Anti Mouse Interferon Gamma Monoclonal Antibody,Biotin
CABT-51777RM
Creative Diagnostics
0.2 mg
EUR 920.4
IFN gamma,Mouse
E34M052M
EnoGene
20 μg
EUR 155
anti- AMPK gamma 1 antibody
FNab00379
FN Test
100µg
EUR 606.3
Mouse Anti Human Interferon Gamma Monoclonal Antibody,APC
CABT-48955MH
Creative Diagnostics
100 TEST
EUR 1132.8
Mouse Anti Human Interferon Gamma Monoclonal Antibody,RPE
CABT-48961MH
Creative Diagnostics
100 TEST
EUR 920.4
Mouse Anti-Human IgG2 (Fc, gamma 2 epitope) Antibody
abx023363-1mg
Abbexa
1 mg
EUR 777.6
Mouse Anti-Human IgG2 (Fc, gamma 2 epitope) Antibody
abx023363-400l
Abbexa
400 µl
Ask for price
Mouse Anti-Human IgG2 (Fc, gamma 2 epitope) Antibody
abx023363-80l
Abbexa
80 µl
EUR 675
Anti-EF-1 gamma antibody
STJ92840
St John's Laboratory
200 µl
EUR 236.4
Mouse Anti-Human gamma delta TCR Purified (100 ug)
TA320268
Origene Technologies GmbH
100 µg
Ask for price
Mouse Anti Human Interferon Gamma Monoclonal Antibody,FITC
CABT-48959MH
Creative Diagnostics
0.1 mg
EUR 852
Mouse Anti Bovine Interferon Gamma Monoclonal Antibody,RPE
CABT-51772MB
Creative Diagnostics
100 TEST
EUR 920.4
Anti-AMPK gamma 1 Antibody
39217
SAB
100ul
EUR 479
Anti-AMPK gamma 1 antibody
PAab00379
Lifescience Market
100 ug
EUR 426
Anti-AMPK gamma 1 Antibody
Y058032
ABM
100 µl
EUR 145
Mini Samples Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) ELISA Kit
MEC073Mu-10x96wellstestplate
Cloud-Clone
10x96-wells test plate
EUR 6965.86
Mini Samples Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) ELISA Kit
MEC073Mu-1x48wellstestplate
Cloud-Clone
1x48-wells test plate
EUR 678.84
Mini Samples Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) ELISA Kit
MEC073Mu-5x96wellstestplate
Cloud-Clone
5x96-wells test plate
EUR 3772.51
Mini Samples Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) ELISA Kit
4-MEC073Mu
Cloud-Clone
Mini Samples Mouse Macrophage Inflammatory Protein 1 Gamma (MIP1g) ELISA Kit
MEC073Mu-1x96wellstestplate
Cloud-Clone
1x96-wells test plate
EUR 918.34
Anti-Laminin gamma 1 (M1)
YF-MA13956
Abfrontier
100 ug
EUR 435.6
Laminin Gamma 1 (LAMC1) Polyclonal Antibody (Mouse)
4-PAC082Mu01
Cloud-Clone
Adverse occasions: two small studies reported on mortality; one in every of these additionally reported on severe and different adversarial occasions, however pattern sizes had been too small for small variations to be detected. Therefore, low-quality proof means that the intervention might have little to no impact on mortality and different adversarial occasions. Health-related high quality of life: solely very low-quality proof from one examine is offered. We are unsure whether or not the intervention improves disease-specific high quality of lifetime of sufferers with bronchial asthma. Health-related outcomes: low-quality proof from eight studies means that the intervention might have little to no impact on bronchial asthma management, glycosylated haemoglobin (HbA1c) ranges, blood strain, low-density lipoprotein or whole levels of cholesterol, physique mass index or weight, or 10-year Framingham threat scores.
Low-quality proof from one examine means that the composite scores of threat components for diabetes mellitus might enhance barely with the intervention, however there’s uncertainty about results on ophthalmic medicines or intraocular strain. Psychosocial well being outcomes: no examine investigated psychosocial well being outcomes in a greater than anecdotal means. Health useful resource consumption: low-quality proof for grownup sufferers in three studies means that there could also be little to no impact of the intervention on completely different measures of well beingcare use. Patient-provider communication: very low-quality proof is offered from a single small examine, and we’re unsure whether or not the intervention improves communication measures, such because the variety of messages despatched.